Injection of BSTFA

Chromatography Forum: GC Archives: Injection of BSTFA
Top of pagePrevious messageNext messageBottom of pageLink to this message  By Uberto on Wednesday, November 1, 2000 - 01:36 am:

I wonder if it is detrimental to GC column and MS detector when BSTFA, a derivatizing reagent, at conc. of about 20% v/v is co-injected into the GCMSD system.


Top of pagePrevious messageNext messageBottom of pageLink to this message  By Anonymous on Thursday, November 2, 2000 - 11:29 am:

Change the liner regularly and clip off a short section of the head of the column fairly often and you should be ok. Residue from derivatized samples will tend to accumulate in the liner and at the head of the column, but shouldn't cause problems with the mass spec.


Top of pagePrevious messageNext messageBottom of pageLink to this message  By Anonymous on Friday, November 10, 2000 - 02:32 pm:

We routinely inject 33% BSTFA into our HP5890/5971 GCMS with no problems. Be aware that first injection of a series may derivatize stuff already on your column, use first injection as a clean out. Use solvent delay as appropriate, and obviously don't use BSTFA on a carbowax column.


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