Bisphenole A

Chromatography Forum: GC Archives: Bisphenole A
Top of pagePrevious messageNext messageBottom of pageLink to this message  By Manfred Sengl on Tuesday, April 10, 2001 - 07:14 am:

We are trying to analyze bisphenole A in suspended solids. Ethylacetate seems to be a good extraction solvent but it usually already contains bisphenole A. Does anybody have an idea how to remove traces of bisphenole A from ethyl acetate?


Top of pagePrevious messageNext messageBottom of pageLink to this message  By Anonymous on Thursday, April 12, 2001 - 11:51 am:

Do you mean you are trying to measure how much bis A is in suspended solids? Some type of solid phase extraction might clean bis A out of ethylacetate. You should be able to find another suitable solvent, such as methanol, acetone or THF perhaps. Bis A readily dissolves in them and they don't contain bis A.

If you are trying to develop a GC method, you may find that bis A is difficult to analyze by GC. RPLC/UV @ 280nm, C18 column will work.


Top of pagePrevious messageNext messageBottom of pageLink to this message  By Manfred Sengl on Thursday, April 19, 2001 - 01:55 am:

Yes, we want to know how much bisphenole A is in suspended solids. Can you tell me which type of material might clean bisphenole A from ethylacetate? Other solvent like methanol or aceton are extracting too many by-products, so that we cannot run GC-MS without prior cleaning of the extract.


Top of pagePrevious messageNext messageBottom of pageLink to this message  By Anonymous on Thursday, April 19, 2001 - 04:33 am:

I am not really that familiar with the many different types of SPE materials, but it sounds like you need a bulk extraction system. Perhaps running your ethylacetate through a glass column filled with silica gel would remove bis A. Another method is the old fashioned distillation. Bis A and ethylacetate boil at such vastly different temperatures that you should easily be able to separate them. A Rotovap can do relatively small amounts quickly.

Can't you get ethylacetate without bis A in it?


Top of pagePrevious messageNext messageBottom of pageLink to this message  By manfred sengl on Tuesday, May 1, 2001 - 10:53 pm:

Unfortunately just filtering through silica gel is not the solution - bis A is washed through! And a simple distillation doesn´t help, too - bis A is also transferred.
It seems to be such a simple question, but I didn`t find the adequate answer...


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