Deternination of limit of detection (LOD) via calibration curve

Chromatography Forum: GC Archives: Deternination of limit of detection (LOD) via calibration curve
Top of pagePrevious messageNext messageBottom of pageLink to this message  By Long on Monday, July 19, 2004 - 08:36 pm:

Hello,did anybody heard before the method to determin LOD via calibration curve? How to do this?

Thanks


Top of pagePrevious messageNext messageBottom of pageLink to this message  By vijay on Tuesday, July 27, 2004 - 05:08 am:

Mr. Long,
from the linearity curve find out residual standard deviation and slope.
Now one can derive

LOD = 3.3*residual stdandard deviation / slope.

LOQ = 10*residual stdandard deviation / slope.

FOR finding out resdiual standard deviation one can use MS-EXCEL application. for the selected two sets of variables follow =styex(Y1:Yn, X1:Xn).

i hope this may give some details about your query.

regards
vijayaragavan.v.l.
chennai, India.


Add a Message


This is a private posting area. A valid username and password combination is required to post messages to this discussion.
Username:  
Password: