Trazodone USP method, Impurity problem

Chromatography Forum: GC Archives: Trazodone USP method, Impurity problem
Top of pagePrevious messageNext messageBottom of pageLink to this message  By y.surender reddy on Saturday, July 24, 2004 - 09:51 pm:

I have the USP method of TRAZODONE in which one of the impurity have been eluting at the RT of about 1.6 min.
Here the problem is the Blank peak also eluting at the same RT of the impurity.
Is there any technique to suppress the blank peak or separate the impurity with blank.
Thanks for your advise in advance.


Top of pagePrevious messageNext messageBottom of pageLink to this message  By HIW on Sunday, July 25, 2004 - 10:22 am:

Are you doing LC or GC? (you are posting on GC thread) What type of column are you using (dimensions, brand) and what is your mobile phase. Do you have a structure of the impurity?


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