I work for a semiconductor manufacturer. We are trying to convince the management that we need a GC/MS for organic analysis of various chemicals and gases used in production. I was wondering if anyone could tell me the approximate detection limits being achieved with systems being used elsewhere. Any help you can offer would be greatly appreciated.
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By John Hinshaw on Monday, October 16, 2000 - 09:32 am:
The information you're looking for appeared in the March 2000 GC Connections column in LC/GC North America, pages 296-306. The article isn't currently on the LC/GC website (http://www.lcgcmag.com), but the nomograph from the article can be found here (requires Adobe Acrobat Reader).
Basically it allows estimation of the method detection limits based on injection, separation, and detection techniques. You should read the article for a good understanding of these questions.
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By Anonymous on Monday, October 16, 2000 - 10:25 am:
Thank you for you help.
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By dave on Saturday, November 15, 2003 - 11:53 am:
You also mentioned performing gas analysis, make sure that a GC-MS is also set up to do gas analysis. Currently, I do samples in gas phase from a reactor process using a GC-FID with a gas autosampler.
In addition, GC-MS is a great instrument in that it is superior to GC without a Mass Selective detector in that in can tell the different in analytes that co-elute.
Finally you make want to ask manufacturers about detection limits on GC-MS. Good Luck!
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