By Anonymous on Thursday, August 30, 2001 - 06:52 am:
Does anyone have any ideas about the difference between LC-MS and LC-MS-MS? Thanks.
By Anonymous on Thursday, August 30, 2001 - 11:36 am:
With LC-MS, you are looking at all of the masses coming from a peak in your LC trace. With LC-MS/MS, you select a single (parent) mass from your LC-MS results (often the highest), and the mass spectrometer separates out that parent, fragments it, and then shows the daughter ions from that mass.
If you have two different compounds with different masses that coelute by LC, LC-MS/MS could be used to get the mass spectral data for each compound.
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