By Tony Larson on Wednesday, February 20, 2002 - 07:22 am:
Hi,
I'm interested in purchasing a microsplitter assembly for our LCMS
system. This would be a postcolumn splitter. It would need to split a
postcolumn flow of 0.5-1.0 mL per minute down to 0.1 microliters per
minute (or less, if possible), whilst minimizing peak dispersion. The
outlet pressure from the column is typically 50-200 psi (without the MS
interfaced). The MS interface typically provides an additional
backpressure of 200-300 psi when it is connected to the column at the
given flow rates.
Could anyone recommend a suitable commercially available splitter that would meet this need (UK manufacturer/ distributor preferred)?
Thanks,
Tony
By Anonymous on Thursday, February 21, 2002 - 08:51 am:
what about Valco Instruments? they have some low volumn splitters
By Anonymous on Thursday, February 21, 2002 - 03:52 pm:
I have seen 1/10000 splitters only for prep applications. A 10 cm 0.1 mm MS inlet will give you a delay time of the order of 1 minute. Not good for minimizing peak dispersion of a 0.01 microliter peak.
By Leslie on Monday, March 4, 2002 - 10:59 am:
Most of our LC-MS labs use splitters (Accurate)from LC Packings (San Francisco). These come in a number of split ratios we typically use the 1:5 split for most of our analytical work. I prefer this splitter to the home-made and to the dial variety you can get from Upchurch. I have heard that Upchurch is coming out with a digital that will be in the $300 range.
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