I have VOC detection method (Volvo)head space analysis for leather samples. The method requires FID detector for the quantification of the VOC. Is it possible to identify and quantify the VOC's by using MS ( the colomn is the same)? If not, please, could you give me good reasons ( apart from the deviation from the method )as I need to explain why I can not do the analyses by using the GCMS.
Thanks a lot.

I can't see any reasons why you couldn't do the assay as good or better by GCMS. I am curious why a lab would have GCMS but not FID, though.

Do you think it is possible to detect the same compounds by 2 different detectors???

Is it more useful to have FID than MS ?

If you do a method validation there is no problem for using an MSD instead an FID.
The MSD advantage is just as you said: Identification

Have you studied the L.O.D./L.O.Q with both methods?. Maybe the MSD detector woulb be less sensitivity

You may or may not be able to use the same column depending on the column id and flow rate used in the analysis. If you are using a method promulgated by a standards setting organization (ASTM, DIN, etc.) the answer is definately no, as that is a major, non-approved change to the method.

I'd just document the changes, and document comparable results. Even the FDA allows "in-house" methods as long as the methods or changes have been validated.

VOC's and GC/MS work wonderfully together. Need more evidence, just look at EPA method 524, 8260 etc over 100 different VOC's are identified and quantified down to .5ppb using MS. GC/MS is also great for unknowns. If your just doing 10 or less compounds that have good resolution FID is fine, For more complex mixtures and unknowns GC/MS is the way to go. The only reason for not going with GC/MS as I see it is cost (a good GC/MS cost about as much as my house) and maintenance. A majority of the Head Space methods are FID.