Post column stream splitter for coupling with LC/MS

Chromatography Forum: LC-MS & GC-MS Archives: Post column stream splitter for coupling with LC/MS
Top of pagePrevious messageNext messageBottom of pageLink to this message  By Anonymous on Wednesday, April 16, 2003 - 06:13 am:

Hello,

I´m looking for a flow splitter, which should be installed between LC column and MS. The splitting ratio should be around 10.
I have an offer from LCPackings. They sell two different splitters; one with a fixed splitting ratio and one with a variable ratio.
Has anybody experience with those or other flow splitters (e.g. from ASI) regarding reproducibilty etc.?

Thanks in advance


Top of pagePrevious messageNext messageBottom of pageLink to this message  By Anonymous on Tuesday, July 29, 2003 - 06:46 pm:

Save yourself some money and make a spiltter from a tee and some tubing. By adjusting the length and tubing diameter of the waste side (or the MS side for that matter), you can adjust the split ratio. Often a peice of 0.0025 PEEK on the MS side and a peice of 0.010 on the waste side is used. Be aware, with all splitters, the split ratio will change with changing back pressure (like when running a gradient).


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