We want to determine the molecular mass of oligonucleotides (up to 30mer) using our 8year old Quattro. Is this possible? We do not have a Maldi TOF system which seems to be used by most researchers today. Any help would be appreciated.
Thanks!
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By ves on Friday, August 1, 2003 - 06:05 am:
I think Micromass has a software package that will deconvolve electrospray spectra of proteins to give a mol-mass.
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By mgb on Monday, August 4, 2003 - 07:11 am:
If you are still looking at this post please see:
Christian Huber, Anal. Chem. 1999, 71, 3730-3739
"Analysis of Nucleic Acids by Capillary Ion-Pair Reversed-Phase HPLC Coupled to Negative-ion Electrospray Ionization Mass Spectrometry"