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Resources for Chromatographers

LC Resources is your resource for information on all aspects of HPLC (and UHPLC!). In addition to training, we provide books, tools, tips, consulting, and more


The LC Troubleshooting Bible

This is a compilation of John Dolan's LC Troubleshooting columns from LC-GC magazine from 1983 through September 2016. It is provided in the form of a Webhelp file that can be read with any browser. All of the articles are included as pdf files in chronological order along with a keyword-searchable index to let you zero in on specific topics of interest.


Chromatography Forum

LC Resources adminsters Chromatography Forum - the most popular and useful chromatography discussion group on the web. And it's easy to use! All discussions are open for reading without signing in or registering. Message boards include:

  • Liquid Chromatography
  • Gas Chromatography
  • LC-MS, GC-MS and other "hyphenated" techniques
  • Sample Preparation
  • Data Systems, Controllers, & Computers
  • Student Projects
  • Around the Water Cooler
  • Announcements
  • Employment
  • Archives (of all past messages)
If you have questions or need advice on participating in Chromatography Forum, please contact us.

Separation Science Associates

Check out our sister site for consulting in technical writing / editing, presentations, business development, marketing communications or expert witness support in chromatography.


Analytical Training Solutions

Analytical Training Solutions is the leading global portal for fundamentals, best practice, troubleshooting and method development training for chromatographic and mass spectrometric techniques. Comprehensive, self-paced online courses and validated learning provides a unique education resource for analytical chemists.


DryLab Chromatography Modeling Software

DryLab® is a powerful tool for HPLC method development. Originally developed at LC Resources, inc, it is now sold and supported by Molnar Institute


USP Column Selectivity Databases

Helps match columns of "equivalent" selectivity for column substitution or identify columns of "orthogonal" selectivity for method development


Mass Spec Training.com

Mass-spec-training.com has trained over 1,000 scientists world-wide in the pharmaceutical, biotechnology, chemical and food industries, in addition to private contract laboratories, government, law enforcement, public health, and environmental sectors.

Principal instructors Frederick Klink and O. David Sparkman have decades of practical experience to share with course participants, providing training that you can use immediately in the lab. Courses are updated regularly to incorporate the latest advances.


UHPLC <-> HPLC Transfer Calculator

Download this Excel spreadsheet to help scale UHPLC separation conditions to legacy HPLC systems (and vice versa!)


Scouting Gradients Calculator

Download this Excel method development spreadsheet to help select conditions for initial gradient scouting runs and to interpret the scouting run results.


Recommended Reading

Classic texts on HPLC and MS are a must for every laboratory. You can order these books from Amazon simply by clicking the book cover images.


Useful Links

A compilation of various useful links for chromatographers: courses, journals, discussion groups, and suppliers. 


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