By Anonymous on Friday, November 3, 2000 - 02:52 pm:
Does anyone have a good method for this compound by HPLC ?
By Anonymous on Monday, November 6, 2000 - 06:40 am:
Are you looking for the residual monomer in Poly Methylmethacrylate or just trying to characterize Polymethylmethacrylate? For the first, I would try Headspace GC using MHE-multiple headspace extraction, if you have that capability. For the second, you would probably use SEC-size exclusion chromatography, that is, if you are looking for molecular weight information!
By Anonymous on Monday, November 6, 2000 - 02:32 pm:
This is simply a quantitation of trace amounts of the ester methylmethacrylate in water samples. Column type? Mobile phase? UV wavelenth? Any ideas out there?
By Ron on Tuesday, November 7, 2000 - 06:08 am:
I realize that you have an LC and wish to use it for the analysis, but you are really talking about a purge and trap GC method to accurately analyze the monomer in water samples.
By Anonymous on Tuesday, November 7, 2000 - 07:24 am:
Yo!
I am assuming you are looking for low levels of residual monomer in aqueous solution.If so then this is a relatively simple analysis, one I have carried out many times. recipe;
15cmx4.6mm id C18 column, type B silica best. eg LUNAC18(2) at 35degC
208nm
gradient from 10% ACN in water to 90%ACN over 24mins.hold 6mins. the high ACN will clean your column of any stabilising agents present.
With a decent detector you should be able to see 5ng on col.
If possible use diode array to see the full impurity picture.
By Anonymous on Tuesday, November 7, 2000 - 09:57 am:
Thank you "Yo"-- very helpful info -- I'll see how it works for me
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