is it possible to determine chloride in a reservoir water sample(yellow color) containing 1500ppm of acetone by IC?

if so, how will the acetone present affect the chloride results?

if not, any other suggestions?

i've tried titrating with silver nitrate using potassium chromate as indicator(yellow color). but the end point(pink yellow)is not obvious.

thanks.

There should be no problem. The acetone at that level should not interfere. I use a Dionex ion chromatograph for chloride analysis ionic, polar and nonpolar organic matrix samples all the time. Yours sounds simple. An isocratic carbonate/bicarbonate MP with suppressed conductivity on auto-recycle mode and Dionex's cheapest and simplest column should do the trick. If you are concerned about organic contaminants they can be easily removed by SPE. Some of my sample contain sulfonated alkylbenzenes. These ionic organics bind to the column. I remove them with SPE cartridges as part of my sample prep.

I do not think Dionex column is cheap at all. Also, if you do not have a Dionex IC system, you could not buy column alone.

Correct, Dionex columns are not cheap. However, some are more expensive than others. Their anion exchange columns for gradient NaOH elution are much more expensive than their columns for isocratic carbonate/bicarbonate elution. The reason I suggested Dionex was that I use one and it works very well for the type of separation originally asked about. I was merely giving the instrumentation columns and conditions I use. I am not so sure that columns are specific to chromatograph manufacturers. I think I should be able to use, other than Dionex columns, on my Dionex HPLC. I might also be able also use a Dionex column on other manufacturers equipment such as a Waters HPLC with their conductivity detector. Has anyone ever tried to cross ion exchange columns with ion exchange HPLC manufacturers?

Swapping columns to different systems shouldn’t be a problem. More of a concern is if the HPLC system you want to use can handle the highly buffered mobile phases. The Dionex IC is just a HPLC system designed to handle sodium hydroxide and hydrochloric acid eluents, among others. If you’re interested in giving your system a try, check with the manufacturer to see if the system (pistons, seals, etc.) can handle the eluents. Other things are obviously incompatible, stainless steel and NaOH for example. The manual for our Spectrasystem P4000 HPLC is limited in regard to the effects of different solvents, but it looks to me like I could use the typical IC eluents without trouble. Having said all that, stay with the Dionex products if you can. Dionex has found a niche in IC analysis, and they produce good equipment for that purpose. Our old model 4000 is still working well after 15 years.

Hamilton Company has IC columns similar to Dionex IC column. Please visit www.hamiltoncompany.com, there are many application notes regarding chloride analysis.

Good luck!

I am sorry that I did not explain clearly last time. You can use Dionex column with any HPLC system, the problem is Dionex will not sell the IC column alone unless you have their IC system. Hope they changed policy now.

Effect of Organics in ion chromatography analysis