By Anonymous on Thursday, April 5, 2001 - 06:27 am:
In a chiral hplc analysis of a racemic drug can one take it for granted that the enantiomeric peaks represent equal concentration? Suppose I inject 80 ng of a racemic therapeutic can I assume that each eantiomeric peak (area) represent 40 ng.?
Thanks for clarifying
By DR on Friday, April 6, 2001 - 01:46 pm:
If you can resolve the enantiomers (chiral separation), their relative peak areas will tell you if the mixture is racemic or not.
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