By Anonymous on Monday, April 16, 2001 - 07:30 am:
The pKa values of analytes (especially pharmacecuticals) are very helpful during method development. However, many are not listed in Merck Index. I would like to know where to look for them (pKa) in addition to Merck Index.
Many thanks in advance.
By B.Buglio on Monday, April 16, 2001 - 08:06 am:
Try "Analytical Profiles of Drug Substances": A
multivolume publication of Academic Press.
By Kostas on Thursday, April 19, 2001 - 03:33 pm:
The Chem Web site has a great number of experimentaly calculated pka values. Furthermore, there is a software called "Pallas" that you can design structure and calculates the theoritical(s) pKa.
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