Ciral analysis of clemastine.

Chromatography Forum: LC Archives: Ciral analysis of clemastine.
Top of pagePrevious messageNext messageBottom of pageLink to this message  By Waldek Cejmer on Tuesday, July 3, 2001 - 05:59 am:

I'm a analytist in firm which is contract manufacturer of API’s for pharmaceutical industry.
Presently I have problem with analysis of the separation degree of clemastine fumarate enantiomers. Regarding this I'm are looking for a suitable HPLC chirl column. Can ypou help me?.


Top of pagePrevious messageNext messageBottom of pageLink to this message  By Pet on Thursday, July 5, 2001 - 07:00 am:

Hi Waldek,

I have analyzed enantiomers of Ketamine before using a Chiral-AGP column that we bought from ChromTech of Sweden via one of it's distributors in Asia. I believe the distributor in USA is Advanced Separation Technologies Inc. in NJ. However, we bought ours a couple of years back, so I don't know if the distributorship in USA has changed since then.

I believe there are also Chiral column for GC separation. If your sample is not heat labile, perhaps you can consider that, too.

Good Luck

Pet


Top of pagePrevious messageNext messageBottom of pageLink to this message  By B.Buglio on Sunday, July 15, 2001 - 06:12 pm:

Chirbase (www.chirbase.u-3mrs.fr/chirbase) has a
chromatographic system for clemastine enantioners.
Chirbase is a fee based molecular database
consisting of thousands of chiral separations
HOWEVER you get one free application. I’ve not
used it and would be interested in your feedback.


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