By Anonymous on Wednesday, October 23, 2002 - 12:03 am:
Deal all,
we have a new product that comprised of Niacin and Lovastatin . I want to analyse this two compounds at the same chromatogram and I hope it won't take a long time. but I found it is a little difficult . because Niacin is water soluable very easily , however Lovastatin is unsoluable .so the Niacin is weak reserved and lovastatin is relatively strong reserved. I have tried ion-pair chromatography . but they are not so ideal . do anybody have a good sugestion for this?
Thanks !
Gavin Chan
By Cris on Wednesday, October 23, 2002 - 08:13 am:
Deal all,
we are searching information about vitamin's analysis by HPLC. We have Eclipse XDB-C8,4.6cm x 15 cm column.Somebody wants give us some references about it.
We need to know the methodology (sample treatment).
Thanks
By Anonymous on Wednesday, October 23, 2002 - 08:26 am:
Cris - The first place I would look would be the USP. Although these methods are not always the best they give you a starting point for sample preparation. The USP has methods for all water soluble vitamins as well as fat soluble.
Mel
By jayesh patel on Tuesday, April 27, 2004 - 04:05 am:
Deal all,
we are searching information about lovastatin's analysis by HPLC and/or tlc. We have shimadzu hplc system.Somebody wants give us some references and suggestions about it.
We also need to know the methodology of sample preparation for analysis from fermentation broth.
Thanks
By Uwe Neue on Tuesday, April 27, 2004 - 04:50 pm:
Here is a method:
http://www.waters.com/pdfs/YMC95D.pdf