I'm told to check the pH of a compound and then pKa for HPLC separation. I have prepared the saturated solution and measured the pH. Is this methodology is correct? Do the compound required to get completely dissolved in water.?
![]()
![]()
![]()
![]()
By Anonymous on Monday, December 23, 2002 - 08:00 am:
Filter it then do a titration. What is the pH?
![]()
![]()
![]()
![]()
By Anonymous on Monday, December 23, 2002 - 07:28 pm:
Why titration? pH of filtered soltuion is 5.0
My doubt is , Is it required to completely dissolve by any means, ie can I add some other solvent say methanol , in order to dissolve and then test for pH.
![]()
![]()
![]()
![]()
By Anonymous on Tuesday, December 24, 2002 - 02:46 pm:
No, don't add solvent. You got the pH.
How do you get the pKa without titration?