Response factor for Refractive index detectors

Chromatography Forum: LC Archives: Response factor for Refractive index detectors
Top of pagePrevious messageNext messageBottom of pageLink to this message  By Anonymous on Monday, January 13, 2003 - 11:39 am:

Could anyone please tell me how the response factor is calculated for a refractive index detector?


Top of pagePrevious messageNext messageBottom of pageLink to this message  By jabarrow on Monday, January 13, 2003 - 02:14 pm:

I have the same question.


Top of pagePrevious messageNext messageBottom of pageLink to this message  By Einar Pontén - SeQuant AB on Monday, January 13, 2003 - 04:06 pm:

The response factor (RF) is often used as the quota between the response and the concentration, assuming that the intercept is zero.

RF = response/concentration

derived from
y = kx + yo
k = y/x - yo
intercept = yo = 0
k = y/x


Top of pagePrevious messageNext messageBottom of pageLink to this message  By Anonymous on Tuesday, January 21, 2003 - 01:02 pm:

For refractive index detector rf is often not
linear. If it is not linear for your range of concentration you have to use a calibration curve.


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