By Kris Procek on Wednesday, July 9, 2003 - 05:47 am:
Hi All,
I was the board about two months back, chewing the ear of anyone who would listen about setting up system suitability monitoring for our system here at work, and I was wondering, just out of interest if anyone else is involved in the seperation of Irganox and Irgafos additives used in the Polymer Industry?
If so, what conditions do you use for the separation??
We are currently running a RP Waters C18 microbondapack column, using a 7% H2O:93% MeOH mixture buffered with 0.01% Glacial Acetic Buffer.
Thanks in advance for any replies.
Kris
By Anonymous on Wednesday, July 9, 2003 - 07:58 am:
A C18 column is too retentive for these compounds. An endcapped C8 column would be a better choice. ZirChrom's PBD column would probably work as well.
By Anonymous on Wednesday, July 9, 2003 - 01:16 pm:
Take a look at ASTM D1996-97. As I recall, it is a gradient method that will separate many different Phenolic Antioxidants an additives.
Regards,
Chris
By Anonymous on Wednesday, July 9, 2003 - 03:16 pm:
uBondapak C18 is much less retentive than any C18, and less retentive than most C8 even. No need to consider a C8 if you are successful.
By K.H.W. on Wednesday, July 9, 2003 - 10:46 pm:
Maybe this gives some help, it describes HPLC of antioxidants:
http://www.chem.agilent.com/scripts/LiteraturePDF.asp?iWHID=32779
By Anonymous on Tuesday, July 15, 2003 - 12:37 am: