Carboplatin related substance in formulation

Chromatography Forum: LC Archives: Carboplatin related substance in formulation
Top of pagePrevious messageNext messageBottom of pageLink to this message  By Anonymous on Monday, August 11, 2003 - 05:15 am:

Dear Friends ,
Can any one suggest a reliable method for estimation of related substance /degradation products of Carboplatin injection, since hydrolysis degradation products of carbo known to exists in equilibrium and there is no reliable method given in any official methods for total impurities.

Regards


Top of pagePrevious messageNext messageBottom of pageLink to this message  By ananda on Monday, August 11, 2003 - 01:54 pm:

can you give us more details about the drug 'cause I am lazy to go anywhere to read about it. Is it like Cisplatin ; an inorganic cmplx?

Thanks!


Top of pagePrevious messageNext messageBottom of pageLink to this message  By Anonymous on Tuesday, August 12, 2003 - 04:18 am:

http://www2.waters.com/watprod.nsf/Newdocs/970245


Top of pagePrevious messageNext messageBottom of pageLink to this message  By Anonymous on Monday, August 18, 2003 - 04:53 am:

Yes the carboplatin is analogue of cisplatin and its chemical name is [cis-diammine(cyclobutane-1,1-dicarboxylato)platinum].


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