Impurity / Related Substances for Ketoconazole

Chromatography Forum: LC Archives: Impurity / Related Substances for Ketoconazole
Top of pagePrevious messageNext messageBottom of pageLink to this message  By lime on Friday, September 12, 2003 - 02:33 am:

Hi all. I need a HPLC method for impurity of ketokonazole.Neither USP/BP doesn't include a method. EP has one ( is called related substances )and gives 4 impurities. But related substances method doesn't talk about the impurities.

So, could you give me some information please ? If related substances and impurities are the same thing in general or this is aspecial circumstances 4 ketoconazole and can i find a quantative method for imp. of ketoconazole.

Lime


Top of pagePrevious messageNext messageBottom of pageLink to this message  By bookoon on Monday, October 20, 2003 - 11:53 pm:

rel substanccs and rel impurities are pretty much the same thing..so go ahead with EP method.


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