I have been using an Alltech ELSD ("Evaporative Light-Scattering Detector") for quantitation of HPLC peaks. I have worked out a pretty simple means of "linearizing" the signal and quantitating both known and (to a limited extent) unknown components. I have no idea whether this is a new approach or whether it or something similar has been published.

I probably should have done a literature search before I began this work, but initially it was only to be qualitative work -- then the objectives changed. I am initiating a literature search now.

However in my experience it is always better to "ask someone who knows". So I'm asking:

Does anyone know of any "standard" or previously published procedures for quantitating the peaks detected with an ELSD?

Alltech has a Technical Note titled "Linearity" that discusses linearity and the Alltech ELSD. You can request it over email by visiting their website: www.alltechweb.com
The note is not an actual journal article/reference, but it might help.

Bruce,
ELSD detectors were first commercially available in the early 1980`s.ACS/POLYMER LABS
-VAREX/ALLTECH-SEDEX are possible sources of the info on linearity or more correctly the non-linearity of light scattering detectors.

Follow-up to original posting:
So far a search of the WWWeb has provided no information on the non-linearity or how to deal with it.
I have not located a technical note on the Alltech web site that specifically addresses linearity of the ELSD, and if someone could give me a number for that note, I would appreciate it.
I have printed off a number of Alltech's "posters" on the ELSD, and have spoken to a tech. rep. there who said that in her experience the ELSD was fairly linear. It appears from the Alltech literature that they sometimes draw a straight line through the calibration points and go with that. That is probably acceptable at times.
I will continue to explore web resourses while our research librarian goes through the printed literature.
Thanks.