How do you determine the S/N? Do you measure the Noise in presence of analyte of interest or independently (by injecting blank)?
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By B.Buglio on Monday, September 27, 1999 - 08:59 pm:
Run the analyte at a low concentration and high
attenuation. Measure the peak height . Select a
stable segment of baseline. Draw parallel lines to
encompass the + and - deflections. Measure the
distance betwwen the parallel lines. The S/N ratio
at the given concentration is the analyte peak
height /noise peak h
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