By Anonymous on Thursday, February 12, 2004 - 02:33 pm:
Hello,
We are using 1.0%Formic Acid in Water as our mobile phase and 0.1%Formic Acid in Methanol as our organic phase. Our question is how do we prevent build-up of the formic acid on the ion sweep cone, spray cone, and the ion transfer capillary? We are using a LCQ Advantage/Mass Spec.
Thanks
By Anonymous on Friday, February 13, 2004 - 12:08 pm:
Formic acid is volitile (that is one of the reasons you are using it). Why do you think it is "building up" on your parts?
By Anonymous on Sunday, February 15, 2004 - 11:49 pm:
Hello, Anonymous #1
any informations about your method and your analytes?
Note that a low concentration of formic acid (1-10 mM) is usually sufficient for a good chromatography and ionization in an electrospray source.