This is maybe a silly question, but I and a colleague thougt about it and don't know which is the best option.

We have to report, on the one hand, the concentration of 1 component in a mixture, and on the other hand the total concentration (the sum of 4 concentrations). We have 4 individual cal curves and a linear cal curve for the sum of 4 (the software allows to do this).

So we can quantify total concentration in 2 different ways:

1-by manually doing the sum of the 4 individual reported results, or

2-from "total curve"

Depending on the way, we obtain 2 different results (which is logical, I know)- slightly different, but in some cases this could lead to exceed LMR (regulation) or not.

Our question is: which way of quantification gives a more accurate result for calculating total concentration and why?

Thank you in advance

Do you know the exacts components of the mixture, if so, make something you know to check which one may be more correct. If you do not know the components, try to guess to make something which may be most similar to your compounds to have a test.

good luck,


jin

Yes, I think like jin, find the accuracy and maybe also the precission of each method, which one is better, choose it.

Thank you, I'll do it

Carmen