By Alan Knaggs on Friday, October 22, 1999 - 08:30 am:
I am looking for a hplc method for the determination of bethanechol chloride in a pharmaceutical preparation.
Anyone out there got any ideas.
By TOM on Tuesday, January 18, 2000 - 04:04 am:
If you do not want to analyse very small quantities, a ion-pairing, RP 18 method with PIC A reagent and ACN/Water, 50/950 will do. Detection at 200 nm or less.
Much better is HPCE with indirect UV detection.
By cDugayo on Monday, March 22, 2004 - 07:08 am:
I am looking for good column besides the one recommended by USP to be used for Determination of Bethanechol Chloride by ion chromatography. I need your suggestions.
By Chris Pohl on Wednesday, March 24, 2004 - 02:32 pm:
Not sure which column is specified but the IonPac CS17 from Dionex should be a good choice for this application since it gives excellent peak shape for small organic cations such as Bethanechol (although I don't believe we have specifically evaluated this compound on the CS17). Please let me know if you would like us to evaluate this columns performance with Bethanechol.