Recent problems with analytical Waters XTerra RP 18 and MS coloums

Chromatography Forum: LC Archives: Recent problems with analytical Waters XTerra RP 18 and MS coloums
Top of pagePrevious messageNext messageBottom of pageLink to this message  By dirk on Wednesday, June 9, 2004 - 02:19 am:

We face most recently some severe challenges with Waters XTerra columns. Bad perfomance and bad batch to batch reproducibility. Did someone make a similar experience and wishes to comment?

Thanx


Top of pagePrevious messageNext messageBottom of pageLink to this message  By Anonymous on Wednesday, June 9, 2004 - 05:40 pm:

I had three XTerra columns from three diferent lots and all of them showed different retention time for my parent compound (the difference was over 15% and I started with brand new columns). What is going on? is it my compound or what. I always equlibrated the columns for at least 30 minutes and did multiple injections).


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