Anybody have any recent experience in designing a layout for an analytical chemistry laboratory to support about 125 R&D employees, including pilot facilities? We support consumer products and OTC pharmaceuticals R&D, have 7 GCs (two connected to MSDs) and 5 HPLC units (two are DAD, and one of those has MSD), as well as FTIR, ICP, nitrogen analyzer, spectrophotometer, 8 fume hoods, etc. Guidelines would be 4000-5000 square feet, rectangular, which includes office space for the staff. I would be gladly welcome any ideas.
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By Steve on Thursday, May 20, 1999 - 05:05 pm:
No matter what else you install, put your instruments on benches allowing free access to the back - e.g., an 18" open alley between penninsular benches is wonderful.
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By Anonymous on Friday, May 21, 1999 - 05:04 am:
Consider using a 30 inch bench height for you instrumentation. Along with the previously mentioned free access to the rear of the units, a lower height makes top access (for repairs, filling of solvent bottles...)possible.
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By Monika on Monday, May 24, 1999 - 08:03 am:
Plan on having the different Instruments in different sections of the building. OSHA regulates the amount of gas that can be stored inside a Lab.For the GC's you will need gases that best be stored outside the building in a sheltered and explosion proof place preferably protected from sun exposure. Plan on maybe the north side of the building for the GC area.
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By John Dolan / LC Resources on Monday, May 24, 1999 - 04:24 pm:
I found a good deal of practical advice in "Guidelines for Laboratory Design: Health and Safety Considerations" 2nd edn L.J. Diberardinis et al, Wiley 1993; Less so with "The Chemical Laboratory: Its Design and Operation" S.J. Rosenlund, Noyes Pubs (Park Ridge, NJ) 1987.
From a practical point of use, we mount all our HPLC systems on MetroMax carts (e.g., from VWR). These are sturdy, flexible in size and layout, and easily moveable. Dropping utilities from the ceiling, you can rearrange the lab whenever you want. Getting behind them for service is easy by pulling them out a little without the lost floorspace of a dedicated service aisle.
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By Brian Paasch on Tuesday, May 25, 1999 - 03:57 pm:
We built our lab about two years ago. The instrument benches are two long islands down the middle of the lab, both split with 18" service alleys with the main bench height at 30". The contractor wanted us to use carts but we fought for the solid benches and we love the result.
-brian paasch
Genentech, Inc.
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