By ylyuen on Friday, August 20, 2004 - 09:02 pm:
Hi! good day.
i'm currently trying to develop a method for glibenclamide and metformin hcl in a gliben/met tablet. i do have individual method for each of the active but they are not applicable as both of them tend to elute out with the same retention time. i know that both of the molecular structure are quite similar and it is difficult to retain both of the active. Do anyone have any suggestion on the method?
TQ!
yenle
By Ananymous on Saturday, August 21, 2004 - 07:28 am:
hi ylyuen,
i would like to know the seperation method of metformin and its impurity cyanoguanidine on Partisil SCX column.
waitg for ur reply.