By Mary Wanzit on Friday, January 21, 2000 - 02:35 pm:
I need to develop an LC assay for Aspirin (acetylsalicylic acid) and its metabolites (salicylic acid and salicyluric acid) in plasma and urine. Does anyone have some info with which I could start? I found some literature, but they are all ~20 years old. I heard that Aspirin is easily hydrolyzed to salicylic acid. Is there any method to prevent this process? Thanks for your time and help!
By Anonymous on Friday, January 21, 2000 - 07:24 pm:
Simultaneous determination of acetylsalicylic acid and salicylic acid in human plasma by high-performance liquid chromatography
Author: Kees, Frieder; et al
Source: J. Chromatogr. B / Year: 1996 / Volume: 677 /Page: 172
By lisa on Monday, January 24, 2000 - 08:14 am:
If anyone has read this article, do you know if it's applicable to whole blood as well as plasma?
Thanks
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