My laboratory is looking to find a HPLC method for the separation of Opiates (mophine, codine, oxycodone, etc). The USP method that our laboratory currently has as a reference uses THF. We would like to avoid using THF if possible.
If anyone has a method that they are currently using or know of a reference to one that would be helpful.
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By Anonymous on Tuesday, February 29, 2000 - 07:12 pm:
Simultaneous Determination of Morphine and Codeine in Blood and Bile Using Dual Utralviolet and Fluorescence High-Performance Liquid Chromatography
Crump, Kerryn L.; et al
J. Anal. Toxicol. / Year: 1994 / Volume: 18 /Page: 208
Determination of morphine and codeine in plasma by HPLC following solid phase extraction
Freiermuth, Michel; et al
J. Pharm. Biomed. Anal. / Year: 1997 / Volume: 15 /Page: 759
Simultaneous determination of Codeine, Norcodeine, and Morphine in biological fluids by high-performance liquid chromatography with fluorescence detection
Chen, Zhao Rong; et al
J. Chromatogr. / Year: 1989 / Volume: 491 /Page: 367
Simultaneous determination of 6-monoacetylmorphine, morphine and codeine in urine using HPLC with combined ultraviolet and
electrochemical detection
Gerostamoulos, Jim; et al
J. Chromatogr. / Year: 1993 / Volume: 617 /Page: 152
HPLC investigation of the inheritance of major opium alkaloids
Khanna, K.R., et al
Planta Medica / Year: 1986 / Volume: April /Page: 157
Simultaneous Quantification of Ethylmorphine O-Deethylase and N-Demethylase Activity by HPLC
Jarvi, Eric J., et al
J. Chromatogr. / Year: 1986 / Volume: 377 /Page: 261
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By ohmacht on Thursday, March 2, 2000 - 03:18 am:
Det. of opium alkaloids from gum opium and poppy straw:
Krenn et al. Chromatographia Vol.47(1998)P.21
(A second part of this paper - sep. on non-porous stationary phase - will be published in the same journal soon.)
Best regards.
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