/ Virtual On-Site: Bioanalytical LC-MS/MS
should take this course?
This course is designed to provide basic knowledge
applications of LC-MS to the analysis of drugs in metabolites in
biological extracts. Although no previous experience with HPLC is
necessary, the course will be especially valuable to those with some
does it cover?
"Bioanalytical LC-MS/MS” is a two-day course
explaining the principles of mass spectrometric detection, the design
and operation of mass spectrometers, and the interfacing of the MS to
the liquid chromatograph to obtain both qualitative and quantitative
data. This two-day course covers:
operation, including the operation of the most popular LC-MS interfaces
a quadrupole mass filter works
calibration and optimization
production, fragmentation and detection
in MS, MS-MS and MS-MS-MS modes
determination by product ion analysis
development and validation
to get the most from your LC-MS
will I get from this course?
will learn how a mass spectrometer works, the
limitations) of adding mass spectrometric detection to your liquid
chromatographic analyses, and how to use MS to approach separation and
detection problems intractable by other methods. By understanding the
central roles of the LC-MS interface and the molecular ion, you will
have a solid grounding on which to further build your LC-MS expertise.You will
learn how to chose the appropriate separation technique for
your application and how to select the best chromatographic mode to
meet your separation goals. You will
learn how to develop and optimize an LC method and how to troubleshoot
it when problems occur. You will learn how to handle columns to achieve
good performance and satisfactory lifetime. The focus of this course
will be on practical guides and tips to achieve successful biomolecule
When is the course available?
course is presented for groups of 10 - 30 people either "on-site" at
your facility or "virtual on-site" using Citrix GoToMeeting service.
On-site presentation is two full days. Virtual On-Site is six 2.5-hour
sessions (typically 2 or 3 sessions per week). The usual lead time to
schedule a course is approximately 4-6 weeks.
course is taught as an in-house
only and can be customized to meet your specific needs. To
discuss in-house course options, call (971) 259-8195
or send us an
with a brief
description of your training needs, and we'll call you with details.
What topics are covered?
course content can be tailored to your specific needs. A typical
schedule looks like this:
Basics of Quadrupole Instrumentation
Calibration and Tubing