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LC Problem Guide

My system died is a common laboratory lament. Use this guide to find out what broke and how top fix it.

Keywords: troubleshooting guide, references, divide and conquer, pressure problems, rules of thumb, low pressure, leaks, chromatographic problems, baseline , retention time, noise, drift, t0 changes, mobile phase, column, sample, split peaks, peak shape

LC-GC 10(7) 508-514 (1992)

John W. Dolan