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Solvent Changeover and Column Equilibration

The intuitively simple process of switching mobile phases may be more complex than it first appears.

Keywords: solvent changeover; column equilibration; equilibration volume; solvent type; ion pairing; avoid water; bonded phase collapse; flushing

LC-GC 14(10) 860-864 (1996)

Derek L. Southern, and John W. Dolan