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Anticipating Problems with a New Method

Some methods are trouble just waiting to happen.

Keywords: readers' questions, compendial methods, column failure, high pH, column stability, backpressure, column problems, type A silica, type B silica, carbon loading, endcapping, column life expectancy, column costs; 

LC-GC 15(5) 424-428 (1977)

John W. Dolan

erratum: pKa phosphate is 2.1, 7.2, and 12.3