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Scaling Gradient LC Methods to LC-MS

Converting methods from LC to LC-MS doesn't have to be difficult

Keywords: gradient, LC-MS, scaling, column dimensions, column diameter, column length, flow rate, particle size, dwell volume, extra-column effects, stainless steel corrosion

LC-GC 18(10) 1034-1039 (2000)

Ryan D. Morrison and John W. Dolan