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Performance Qualification of LC Systems

Chromatographers can use a simple set of tests to check system performance.

Keywords: pump tests; detector tests; system qualification; IQ; OQ; PQ; detector noise; holistic testing; autosampler performance; detector performance; wavelength accuracy; precision; accuracy; documentation

LC-GC 20(9) 842-848 (2002)

Gerald Hall and John W. Dolan

Note that there are several errors in this document. The y-axis scale on Figure 1 should be microvolts, not millivolts. The calculations for Figure 1 are OK, but the operators did not print correctly. The light characters that are displayed instead of operators should be 5 is = (equal); 2 is - (minus); 3 is x (times).