| FILLED-LOOP INJECTION: sample injection technique in
which the loop of the injector is completely flushed out with
sample (using 2 or 3 loop-volumes) before rotating the
valve into the inject position. See also PARTIAL LOOP INJECTION.
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In filled-loop injection, an excess of sample is flushed through the loop during the load process.
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| FITTINGS: refers
to the connectors that join tubing, columns and various
LC modules together.
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This type of fitting is referred to as "zero-dead-volume" (ZDV), because the passage through the fitting is the same diameter as the inside of the tube.
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| FIXED-WAVELENGTH
DETECTOR: a obsolete type of photometric detector having a limited selection of wavelength settings, generally selected by
changing optical filters.
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| FLUORESCENCE DETECTOR: a less common detector that can be quite sensitive and
specific for some compounds.
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Waters 474 Fluorescence Detector
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| FLOW CELL: the
part of a photometric detector through which the sample and mobile
phase pass. The sample is detected in the flow cell.
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 UV Detector Flow Cell Cutaway
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| FRIT: a porous
metal filter that is used to (a) prevent particulates
from entering the LC system with the mobile phase, (b) to
contain the column packing inside the column, or (c) to protect other parts of
the LC system. Frits vary in their porosity from 0.5
micron (in-line filters for protecting the column) to 10
microns (inlet filters or "sinkers" attached to the pump inlet
line).
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